Discussion Forum Assignment: Ethical Consideration in Genetic Screening and Treatment

Accessibility and Long-Term Impact of Gene Therapy

Accessibility and Long-Term Impact of Gene Therapy

by Tam Daws -
Number of replies: 1

The development of treatments for genetic disorders, such as the cystic fibrosis drug discussed in “From the Cystic Fibrosis Gene to a Drug,” highlights the potential of precision medicine. However, one of the biggest challenges is accessibility. These treatments are often expensive, limiting access for lower-income patients. This raises an ethical question: Should life-saving treatments be a right rather than a privilege?

Another key issue is the long-term impact of gene therapies. As shown in “The Costs and Benefits of Treating Gene Defects,” while these treatments can improve quality of life, their effectiveness over time remains uncertain. Are we prepared to handle unforeseen consequences, such as mutations or unexpected side effects?

To address these concerns, governments should implement policies ensuring affordability and continued monitoring of genetic treatments. Without such measures, the gap between those who can afford advanced care and those who cannot will only widen, reinforcing healthcare disparities.


149 words

In reply to Tam Daws

Re: Accessibility and Long-Term Impact of Gene Therapy

by Zhaoyi Sun -
It is an important ethical concern about the accessibility of life-saving genetic treatments. The case of Kalydeco for CF shows the power of precision medicine, but as you pointed out, its high-cost limits access for many patients. This raises the fundamental question that, should healthcare prioritize profit, or should life-saving treatments be a universal right? One possible solution is government subsidies or pharmaceutical pricing regulations to ensure that all patients can access these advancements.
Your point about the long-term impact of gene therapies is also critical. Some gene therapies involve permanent DNA modifications, and unintended consequences could emerge years later.

100 words